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Philip I. Marcus (June 3, 1927 in Springfield, Massachusetts〔Philip I. Marcus. Time, Travels, and Travails with the Interferon System. Journal of Interferon & Cytokine Research 27:971–983 (2007).〕 – September 1, 2013 in Farmington, Connecticut) was an American virologist and a leader in the field of interferon. From 2003 he was a Board of Trustees Distinguished Professor of Molecular and Cell Biology at the University of Connecticut.〔http://advance.uconn.edu/2003/030421/03042101.htm〕 Philip Marcus received his education directly as a result of the G.I. Bill. He took some courses in general education and engineering while serving in the United States Army Air Force in 1945-46 then, after a year abroad as part of the US occupation forces in Europe, left the USAAF and studied for his BS at the University of Southern California, his MS at the University of Chicago (where he first met Leó Szilárd) and earned his PhD from the University of Colorado (Denver) where he also was an Associate Professor and worked with Theodore Puck.〔Philip I. Marcus: Curriculum Vitae〕 ==Research== In 1955 he co-authored a paper on "the first practical and efficient method for growing colonies from individual animal cells", known as the clonogenic assay, which is still used today.〔http://advance.uconn.edu/2005/050907/05090710.htm〕〔Puck TT, Marcus PI. A Rapid Method for Viable Cell Titration and Clone Production With Hela Cells In Tissue Culture: The Use of X-Irradiated Cells to Supply Conditioning Factors. Proc Natl Acad Sci U S A. 1955 Jul 15;41(7):432-7. URL: (PNAS )(JSTOR )〕 He was also the first person to clone HeLa cells,〔TWiV 197: Cloning HeLa cells with Professor Philip I Marcus (URL Podcast ) 〕 and was editor-in-chief of the ''Journal of Interferon and Cytokine Research'' for 18 years.〔http://clas.uconn.edu/news/inthenews_2011_10_07.htm〕 Marcus gives credit to Leó Szilárd〔William Lanouette, Genius in the Shadows, pp.296-98〕 for inspiring this achievement in both an interview for ''Genius in the Shadows'', a biography of Szilárd, and in the ''This Week in Virology'' 2012 interview.〔Transcript of TWiV interview@http://www.twiv.tv/TWiV197-082612.pdf〕〔http://www.twiv.tv/TWiV197-082612.pdf〕 Dr. Marcus' further career included positions at the Albert Einstein College of Medicine, the Cold Spring Harbor Laboratory and the Salk Institute. The primary focus of his research from 1966 until his death was in the field of interferon research.'His Virus and Interferon Research Laboratory at UConn's Torrey Life Sciences Building became the leading proponent of the theory that double-stranded ribonucleic acid, dsRNA, is the inducer of interferon, and that just one molecule of dsRNA is enough to induce interferon production in a cell, thus activating a cell's response to a virus.'〔http://today.uconn.edu/blog/2011/10/pioneer-in-interferon-research-honored/〕 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Philip I. Marcus」の詳細全文を読む スポンサード リンク
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